Version 4.4 (November 2019)
Changes made to PanelPlex™ since the previous (4.1) release:
- Improved error messages.
- PanelPlex will provide partial results for some runs with failed panels.
- Improved some memory issues with large runs.
- Improved processing of large result zip files.
- Improved page load times.
- Other miscellaneous bug fixes.
Version 4.1.1 (September 2018)
Changes made to qPCR CopyCount since the previous (4.0) release:
- Added QuantStudio 3 Data processor
Changes made to PanelPlex™-NGS since the previous (4.0) release:
- Added performance and efficiency enhancements.
- Updated the NGS input format to specify a junction range instead of a single position.
Version 4.0 (May 2018)
Added new product: PanelPlex™-NGS
- Allows for multiplexes up to 50plex (later versions will increase this limit)
Changes made to PanelPlex-MDx since the previous (3.2.1) release:
- Changed name of product from PanelPlex to PanelPlex-MDx. Clarifies that this product is for the consensus design of molecular diagnostics for infectious diseases.
- Added functionality to save all the input parameters for a given run. This allows accurate documentation of how each run was performed.
- Added functionality to run PP-MDx using the input parameters file. This allows runs to be repeated exactly with minimal opportunities for user input error.
- Improved default settings in PP-MDx.
- Scoring weight for G-quartet penalty increased.
- Added functionality to download all results as a .zip file.
- Page load times improved.
- Improved layout of Next and Back buttons on each page.
- Genomes with lower case letters (such as Zika virus) now correctly shown in the Coverage section of the output.
- Improved automatic keystone selection
Changes made to ThermoBLAST-CE since the previous (3.2.1) release:
- Increased number of CPU cores devoted to ThermoBLAST jobs from 14 to 33. Resulting in runtime improvement.
- Fix ability to add and remove accessions from an existing ThermoBLAST playlist
- Fixed issue where downloaded amplicon had 1 extra nucleotide on the 5’-end and was missing 2 nucleotides at the 3’-end.
- Functionality for automatic detection and deletion of duplicate accessions.
- Fixed functionality for combining pre-existing playlists.
- Increased memory limits to allow for larger playlists to be handled.
- Amplicon detection algorithm improved to both go faster and also to detect more amplicons. In the previous version some weak binding primers would not be detected as amplicons.
- Minor bug fixes and optimizations
- Several new playlists added (e.g. Vaginal microbiome, GEBA).
- Known remaining issue: Within the “View Playlist” page if you try to edit the playlist then the program terminates. Workaround: Log back in and edit the playlist from the “Playlists you created” page.
Changes made to qPCR CopyCount since the previous (3.2.1) release:
- Added support for MJ Research data format.
- Non-permanence of data implemented for CNV
- At rest encryption added for CNV data
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